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KMID : 0363320100310030578
Journal of Korean Oriental Internal Medicine
2010 Volume.31 No. 3 p.578 ~ p.585
The Relationship between Coldness of Hands and Feet and the Erythrocyte Deformability in Stroke Patients
Park Joo-Young

Leem Jung-Tae
Park Su-Kyung
Woo Su-Kyung
Kawk Seung-Hyuk
Jung Woo-Sang
Moon Sang-Kwan
Cho Ki-Ho
Park Sung-Wook
Ko Chang-Nam
Abstract
Objectives:Coldness of hands and feet has been regarded to be associated with blood circulation. This study was performed to assess the correlation between erythrocyte deformability and coldness of hands and feet.

Methods:145 patients who had taken an erythrocyte deformability test were selected for this study among hospitalized patients within 4 weeks after their cerebral infarction at the Internal Medical Department at Kyunghee Oriental Medical Center from August 2008 to August 2009. We divided the selected patients into two groups, with and without of coldness of hands and feet groups. The two groups were compared on risk factors for atherosclerosis and examined for variables including erythrocyte deformability.

Results:1. On demographic variables of the patients, only body mass index was significantly lower in the coldness of hands and feet group than the control group. There was no significant difference of the rate of hypertension, diabetes mellitus, hyperlipidemia, ischemic heart disease, smoking, drinking and carotid artery stenosis between the two groups. 2. According to blood test, the coldness of hands and feet group showed significantly lower erythrocyte deformability index than the control group. 3. Body mass index and erythrocyte deformability index showed a close relationship with coldness of hands and feet in multivariate analysis.

Conclusions:The correlation between the erythrocyte deformability and coldness of hands and feet in cerebral infarction patients were decreased erythrocyte deformability participated in the mechanism of coldness of hands and feet.
KEYWORD
Erythrocyte deformability, Coldness of hands and feet, Elongation index, Microcirculation
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